The SqueakNOS (Squeak No Operating System) project is back.
SqueakNOS was an attempt to get Squeak running on x86 pcs without an underlying OS. The aim was to push as much of the hardware interface into the Smalltalk image as possible. There has been no progress since 2001 but now the original team is back and SqueakNOS is quite live and quite kicking!
You can either throw away your installed OS (not yet recommended) or use PC emulators like VMWare for a first test.